Active duty: An activatable fluorescent probe consisting of a peptide, Arg‐Val‐Arg‐Arg (RVRR), and an aminoluciferin fluorophore is designed and prepared for the responsive and activatable detection of furin activity in living cells. This probe is shown to have “off–on” florescence properties, and in the presence of furin in vitro, its fluorescence intensity is increased by a factor of ≈3.58.

中文翻译：

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针对活细胞中弗林蛋白酶活性检测的可激活荧光探针的靶向递送。

主动工作：设计并制备了一种可激活的荧光探针，该探针由肽，Arg-Val-Arg-Arg（RVRR）和氨基荧光素荧光团组成，用于响应性和可激活的活细胞弗林蛋白酶活性检测。该探针具有“关闭-开启”荧光特性，并且在弗林蛋白酶存在下，其荧光强度增加了约3.58倍。