Aiming to overcome the obstacles of power supply requirement and chip usefulness in practice, a low-cost and convenient portable electrochemical sensing device is introduced for the first time, featuring bipolar electrode system, LED read-out, laminated paper-based devices, and low-voltage button cells. The electric circuits of this practical device are constructed on laminating films with copper and conductive carbon tapes, and the reservoirs facilitating chemical reactions are made with chromatography paper. The device is sensitive to electrochemical responses, validated by the demonstrative hydrogen peroxide and enzyme-assisted glucose detection. The business-card-size chip achieves sensitive analyte detection by naked eyes as well as further image processing in both laboratory samples and human serum samples testing, featuring detection limit as low as 1.79 μM and a dynamic range from 10 μM to 10 mM. This new practical design of point-of-care sensing chip entails the properties of facile fabrication, simple usage, high robustness, low power consumption, and accurate sensing showing the attainability of fabricating a useful and portable analytical device.

中文翻译：

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低压驱动的便携式纸质双极电极支撑电化学传感装置

为克服电源需求和芯片实用性的障碍，首次推出了一种低成本、方便的便携式电化学传感装置，具有双极电极系统、LED读出、层压纸基器件和低功耗等特点。 -电压纽扣电池。这个实用装置的电路是在铜箔和导电碳带的层压薄膜上构建的，促进化学反应的容器是用色谱纸制成的。该设备对电化学反应敏感，通过示范过氧化氢和酶辅助葡萄糖检测验证。名片大小的芯片实现了肉眼灵敏的分析物检测以及实验室样品和人血清样品检测中的进一步图像处理，具有低至 1.79 μM 的检测限和 10 μM 至 10 mM 的动态范围。这种新的护理点传感芯片的实用设计具有制造容易、使用简单、高稳健性、低功耗和精确传感等特性，显示出制造有用和便携式分析设备的可行性。