The case study approach provides students with a better appreciation of how scientists solve problems and conduct themselves in the “real world”. When applied to the undergraduate chemistry laboratory, this approach also challenges critical thinking skills and creativity in ways “cook book” experiments very often do not. This approach provides students the opportunity to learn analytical principles in the context of relevant everyday problems, stimulate a sustaining interest, and develop higher cognitive skills and reasoning abilities. The laboratory-based case study described here combines the use of small collaborative groups and a modern instrumental technique, with application to a common consumer product. Students are required to conduct themselves as chemists would, when addressing the problem of product purity claims, and to make a determination based on their experimental results that will be used to direct future action taken by a formulation company. This case study even addresses potential legal exposure issues the company may encounter with the Food and Drug Administration. In that context, students come to realize that a faulty conclusion could potentially have undesirable ramifications. In addition, students are provided with the opportunity to gain useful hands-on experience on instrumentation commonly used in modern analytical laboratories. A “professional” report must also be written by students in journal style format including all relevant data, calculations, and statistical and error analysis. Assessment was made using mixed methods. Results indicate the laboratory was largely successful in meeting its objectives.

中文翻译：

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通过HPLC测定抗真菌药克林喹诺，不是那么纯净的制备：仪器分析化学课程的基于实验室的案例研究

案例研究方法使学生更好地了解科学家如何解决问题以及如何在“现实世界”中开展活动。当应用于本科化学实验室时，这种方法还会以“烹饪书”实验经常遇到的方式挑战批判性思维技能和创造力。这种方法为学生提供了在相关的日常问题中学习分析原理的机会，激发了持续的兴趣，并发展了更高的认知能力和推理能力。这里描述的基于实验室的案例研究结合了小型协作小组的使用和现代工具技术，并应用于普通的消费产品。在解决产品纯度声明问题时，要求学生像化学家那样行事，并根据他们的实验结果做出决定，这些决定将用于指导配方公司将来采取的行动。该案例研究甚至解决了公司与食品药品监督管理局可能遇到的潜在法律风险问题。在这种情况下，学生开始意识到错误的结论可能会带来不利的后果。此外，还为学生提供了获得现代分析实验室常用仪器实用实践经验的机会。学生还必须以期刊形式编写“专业”报告，包括所有相关数据，计算以及统计和错误分析。使用混合方法进行评估。结果表明该实验室在实现其目标方面取得了很大的成功。