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Reinforcing effect of graphene oxide reinforcement on the properties of poly (vinyl alcohol) and carboxymethyl tamarind gum based phase-separated film
Journal of the Mechanical Behavior of Biomedical Materials ( IF 3.9 ) Pub Date : 2018-02-20 , DOI: 10.1016/j.jmbbm.2018.02.021
Indu Yadav , Suraj K. Nayak , V.S. Sharan Rathnam , Indranil Banerjee , Sirsendu S. Ray , Arfat Anis , Kunal Pal

The current study deals with the preparation and the characterization of the PVA-CMT-GO films. The PVA-CMT film was translucent in nature and smooth to touch. The addition of GO resulted in the formation of agglomerated structures. XRD studies suggested that the incorporation of GO increased the average crystallite size. The mechanical properties of the films as determined by stress relaxation studies suggested that all the films were viscoelastic in nature. The drug release study showed a decrease in the amount of the drug release with the increase in the GO content. The PVA-CMT-GO films (without drug) showed certain degree of antimicrobial activity owing to the inherent antimicrobial property of GO. The drug loaded films also showed good antimicrobial property. It was found that the prepared films altered the cell proliferation of the human skin keratinocytes in a composition-dependent manner.



中文翻译:

氧化石墨烯增强剂对聚乙烯醇和羧甲基罗望子树胶基相分离膜性能的增强作用

当前的研究涉及PVA-CMT-GO膜的制备和表征。PVA-CMT膜本质上是半透明的,摸起来光滑。GO的加入导致聚集结构的形成。XRD研究表明,GO的加入增加了平均晶粒尺寸。通过应力松弛研究确定的膜的机械性能表明,所有膜本质上都是粘弹性的。药物释放研究表明,随着GO含量的增加,药物释放量减少。由于GO固有的抗菌特性,PVA-CMT-GO薄膜(不含药物)显示出一定程度的抗菌活性。载有药物的薄膜还显示出良好的抗菌性能。

更新日期:2018-02-20
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