The cover feature picture shows three men on a climbing wall representing molecules binding to a cell with one, two or four binding moieties. To explore avidity effects on immune stimulation and cancer cell binding, chemoselective ligations were used to assemble molecules that mimic the functions of antibodies with various numbers and combinations of immune‐stimulating and cancer‐targeting peptides. More information can be found in the full paper by A. C. Conibear, C. F. W. Becker et al. on page 459 in Issue 5, 2018 (DOI: 10.1002/cbic.201700522).

中文翻译：

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封面人物：针对合成癌症的先天免疫刺激剂可深入了解亲和力效应（ChemBioChem 5/2018）

封面特征图片显示了三个攀岩墙上的人，代表分子与具有一个，两个或四个结合部分的细胞结合。为了探索对免疫刺激和癌细胞结合的亲和力影响，化学选择性连接被用于组装分子，这些分子模拟具有各种数量以及免疫刺激和靶向癌细胞的肽组合的抗体的功能。可以在A. C. Conibear，C。F. W. Becker等人的全文中找到更多信息。就在第5期，2018页459（：10.1002 / cbic.201700522 DOI）。