In this work we report a facile method to prepare a fluorescence active self-healable hydrogel via incorporation of fluorescence responsive ionic block copolymers (BCPs). Ionic block copolymers were prepared via a combined effect of ring opening polymerization (ROP) of ε-caprolactone and xanthate mediated reversible addition–fragmentation chain transfer (RAFT) polymerization. Here polycaprolactone (PCL) was modified with xanthate to prepare a PCL based macro-RAFT agent and then it was utilized to prepare block copolymers with cationic poly(2-(methacryloyloxy)ethyltrimethyl ammonium chloride) (PCL-b-PMTAC) and anionic poly(sodium 4-vinylbenzenesulfonate) (PCL-b-PSS). During the block formation, the cationic segments were randomly copolymerized with a trace amount of fluorescein O-acrylate (FA) (acceptor) whereas the anionic segments were randomly copolymerized with a trace amount of 9-anthryl methylmethacrylate (AMMA) (donor) to make both the segments fluorescent. The block copolymers form micelles in a DMF : water mixture (1 : 4 volume ratio). The ionic interaction of two BCPs was monitored via Förster resonance energy transfer (FRET) and zeta potential measurements. The oppositely charged BCPs were incorporated into a polyacrylamide (PAAm) based hydrogel that demonstrated self-healing behavior and is also highly fluorescent.

中文翻译：

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通过开环聚合和黄药介导的RAFT聚合 制备的基于离子嵌段共聚物的自修复荧光活性水凝胶†

在这项工作中，我们报告了一种通过掺入荧光反应性离子嵌段共聚物（BCP）来制备具有荧光活性的自修复水凝胶的简便方法。离子嵌段共聚物是通过ε-己内酯的开环聚合（ROP）和黄原酸酯介导的可逆加成-断裂链转移（RAFT）聚合的联合作用而制备的。在这里，用黄药将聚己内酯（PCL）改性，以制备基于PCL的大分子RAFT剂，然后将其用于制备与阳离子聚（2-（甲基丙烯酰氧基）乙基三甲基氯化铵）（PCL- b- PMTAC）和阴离子聚（4-乙烯基苯磺酸钠）（PCL- b-PSS）。在嵌段形成过程中，将阳离子链段与痕量的荧光素O-丙烯酸酯（FA）（受体）无规共聚，而将阴离子链段与痕量的9-甲基丙烯酸甲基丙烯酸甲酯（AMMA）（供体）无规共聚。两个片段都发荧光。所述嵌段共聚物在DMF∶水混合物（1∶4体积比）中形成胶束。通过福斯特共振能量转移（FRET）和Zeta电位测量来监测两个BCP的离子相互作用。将带相反电荷的BCP掺入基于聚丙烯酰胺（PAAm）的水凝胶中，该凝胶表现出自愈性能，并且具有很高的荧光性。