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Specific Oxygenated Groups Enriched Graphene Quantum Dots as Highly Efficient Enzyme Mimics
Small ( IF 13.3 ) Pub Date : 2018-02-12 , DOI: 10.1002/smll.201703710 Huan Wang 1, 2 , Chaoqun Liu 1, 3 , Zhen Liu 1 , Jinsong Ren 1 , Xiaogang Qu 1
Small ( IF 13.3 ) Pub Date : 2018-02-12 , DOI: 10.1002/smll.201703710 Huan Wang 1, 2 , Chaoqun Liu 1, 3 , Zhen Liu 1 , Jinsong Ren 1 , Xiaogang Qu 1
Affiliation
Significant progress is achieved for the utilization of graphene quantum dots as enzyme mimics in various biomedical fields recently. Although promising, the biocatalytic performance is far from satisfactory. Here, the rational design and synthesis of specific oxygenated groups enriched graphene quantum dots (o‐GQDs) via a facile oxidation reflux route is reported. These well‐prepared o‐GQDs with uniform size exhibit an ultrahigh peroxidase‐like activity in a wide range of pH values, and their superior performance is verified by using glucose detection as a typical model. Compared with classical nanozymes, these o‐GQDs show multiple times higher enzymatic activity. It is believed that the super facile synthesis strategy can greatly facilitate the practical use of o‐GQDs as enzyme mimics in the future.
中文翻译:
特定的氧化基团丰富了石墨烯量子点作为高效的酶模拟物。
近年来,在各种生物医学领域中,利用石墨烯量子点作为酶模拟物取得了重大进展。尽管有希望,但是生物催化性能远不能令人满意。在这里,报告了通过简便的氧化回流途径合理设计和合成特定的含氧基团富集的石墨烯量子点(o-GQDs)。这些精心准备的大小一致的o-GQD在广泛的pH值范围内均表现出超高的过氧化物酶样活性,并且通过使用葡萄糖检测作为典型模型来验证其优越的性能。与经典的纳米酶相比,这些o-GQD的酶活性高出数倍。据信,超简便的合成策略可以极大地促进o-GQDs在未来作为酶模拟物的实际应用。
更新日期:2018-02-12
中文翻译:
特定的氧化基团丰富了石墨烯量子点作为高效的酶模拟物。
近年来,在各种生物医学领域中,利用石墨烯量子点作为酶模拟物取得了重大进展。尽管有希望,但是生物催化性能远不能令人满意。在这里,报告了通过简便的氧化回流途径合理设计和合成特定的含氧基团富集的石墨烯量子点(o-GQDs)。这些精心准备的大小一致的o-GQD在广泛的pH值范围内均表现出超高的过氧化物酶样活性,并且通过使用葡萄糖检测作为典型模型来验证其优越的性能。与经典的纳米酶相比,这些o-GQD的酶活性高出数倍。据信,超简便的合成策略可以极大地促进o-GQDs在未来作为酶模拟物的实际应用。