Amide linkage containing two nicotinic acid amphiphiles have been investigated for their gel-emulsion and glucose sensing properties. In emulsions, the synthesized materials were used as stabilizers in water medium, whereas organic solvents and/or mineral oils as dispersed phase and water acts as a continuous phase. The gel-emulsions were prepared at room temperature by stirring or shaking, and no heating–cooling arrangement or addition of any other co-solvents or active agents are mandatory. Rheological investigation of these amphiphiles showed mechanical stability of gel-emulsions and its viscoelasticity. Optical images confirmed the existence of network structures in gel-emulsion phase for both amphiphiles. FE-SEM measurement suggests the morphology depends on the solvent:water composition. An XRD study proposed that the arrangements of the amphiphiles in the emulsion state are different. The gel-emulsions formed by the studied amphiphiles are able to entrap and release biomolecules, anticancer drug molecules, and hazards chemicals. These gelator molecules are very sensitive to detect glucose molecules in aqueous solution. The subchronic toxicity of these synthesized molecules has been evaluated as nontoxic on the hematological and biochemical parameters of male Swiss albino mice.

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无毒烟酸衍生葡萄糖传感器的凝胶乳液特性

已经研究了包含两个烟酸两亲物的酰胺键的凝胶乳液和葡萄糖感测特性。在乳液中，合成的材料在水介质中用作稳定剂，而有机溶剂和/或矿物油则作为分散相，而水则作为连续相。该凝胶乳液是在室温下通过搅拌或摇动制备的，不需要加热冷却装置或添加任何其他助溶剂或活性剂。这些两亲物的流变学研究表明凝胶乳液的机械稳定性及其粘弹性。光学图像证实了两种两亲物在凝胶乳液相中都存在网络结构。FE-SEM测量表明其形态取决于溶剂：水的成分。XRD研究表明，乳液状态下两亲物的排列方式不同。由研究的两亲物形成的凝胶乳液能够截留并释放生物分子，抗癌药物分子和有害化学物质。这些胶凝剂分子对检测水溶液中的葡萄糖分子非常敏感。这些合成分子的亚慢性毒性已被评估为对瑞士白化病雄性小鼠的血液学和生化指标无毒。