Chemical Physics ( IF 2.3 ) Pub Date : 2018-02-09 , DOI: 10.1016/j.chemphys.2018.02.011 Katie A. Link , Chia-Yun Hsieh , Aashish Tuladhar , Zizwe Chase , Zheming Wang , Hongfei Wang , Robert A. Walker
Vibrational sum frequency generation (VSFG) and surface tension experiments were used to examine the effects of aqueous phase soluble saccharides on the structure and organization of insoluble lipid monolayers adsorbed to aqueous-air interfaces. Changes in dipalmitoylphosphocholine (DPPC) chain structure as a function of aqueous phase saccharide concentration and pH are reported. Complementary differential scanning calorimetry (DSC) measurements performed on solutions containing soluble saccharides and DPPC vesicles measured the effects of the saccharides on the lipid membrane phase behavior. Data show that the saccharides glucosamine and glucuronic acid induce a higher degree of organization in compressed DPPC monolayers regardless of the saccharide’s charge.
中文翻译:
在水/空气界面处的糖诱导的脂质膜重组的振动研究
振动总和频率产生(VSFG)和表面张力实验用于检查水相可溶性糖对吸附到水-空气界面的不溶性脂质单层的结构和组织的影响。据报道,二棕榈酰磷酸胆碱(DPPC)链结构随水相糖浓度和pH的变化而变化。对包含可溶性糖和DPPC囊泡的溶液进行的互补差示扫描量热(DSC)测量,测量了糖对脂质膜相行为的影响。数据显示,无论糖的电荷如何,糖的葡糖胺和葡萄糖醛酸都可以在压缩的DPPC单层中诱导更高程度的组织。