While supramolecular organisation is central to both crystallization and gelation, the latter is more complex considering its dynamic nature and multifactorial dependence. This makes the rational design of gelators an extremely difficult task. In this report, the assembly preference of a group of peptide-based sulfamides was modulated by making them part of an acid–amine two-component system to drive the tendency from crystallization to gelation. Here, the peptide core directed the assembly while the long-chain amines, introduced through salt-bridges, promoted layering and anisotropic development of primary aggregates. This proved to be very successful, leading to gelation of a number of solvents. Apart from this, it was possible to fine-tune their aggregation using an amphiphilic polymer like F-127 as an additive to get honey-comb-like 3D molecular architectures. These gels also proved to be excellent matrices for entrapping silver nanoparticles with superior emissive properties.

中文翻译：

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从螺旋超分子阵列到凝胶形成网络：基于肽的磺酰胺中的晶格重组和聚集控制可整合新的功能属性†

尽管超分子组织对于结晶和凝胶化均至关重要，但考虑到其动态性质和多因素依赖性，后者更为复杂。这使得胶凝剂的合理设计成为极其困难的任务。在本报告中，通过使一组基于肽的磺酰胺成为酸-胺两组分体系的一部分来调节其组装偏好，从而驱动了从结晶到胶凝的趋势。在这里，肽核指导组装，而通过盐桥引入的长链胺则促进了主要聚集体的分层和各向异性发展。事实证明，这种方法非常成功，导致许多溶剂发生胶凝。除此之外，还可以使用两亲性聚合物（例如F-127）作为添加剂来微调它们的聚集，从而获得蜂蜜。梳状3D分子架构。这些凝胶也被证明是包埋具有优异发射性能的银纳米颗粒的优良基质。