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Metal-Free Iodine-mediated Deoxygenation of Alcohols in alpha-Position to Electron-withdrawing Group
European Journal of Organic Chemistry ( IF 2.8 ) Pub Date : 2018-04-03 , DOI: 10.1002/ejoc.201800051
Maëva M. Pichon 1 , Fabien Stauffert 1 , Luis G. Addante-Moya 1 , Anne Bodlenner 1 , Philippe Compain 1
Affiliation  

The use of a substoichiometric amount of molecular iodine in the presence of PPh3 and pyridine effects a direct deoxygenation of primary and secondary alcohols in positions α to a variety of activating electron‐withdrawing groups, including ketones, esters, amides, imides and nitrile groups.

中文翻译:

无金属碘介导的αα位醇脱氧到吸电子基团

在 PPh3 和吡啶的存在下,使用亚化学计量的分子碘可将 α 位的伯醇和仲醇直接脱氧为各种活化的吸电子基团,包括酮、酯、酰胺、酰亚胺和腈基。
更新日期:2018-04-03
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