In this communication, we developed the first well-controlled Z-RAFT (RAFT = reversible addition–fragmentation chain transfer) mediated polymerization-induced self-assembly (PISA) formulation based on photoinitiated RAFT dispersion polymerization of tert-butyl acrylate (tBA) in ethanol/water (60/40, w/w) at room temperature using a Z-type macromolecular chain transfer agent (macro-CTA). Polymerizations proceeded rapidly via the exposure of visible-light irradiation (405 nm, 0.45 mW/cm²) with high monomer conversion (>95%) being achieved within 1 h. A variety of polymer nano-objects (spheres, worms, and vesicles) with narrow molar mass distributions were prepared by this Z-RAFT mediated PISA formulation. Silver nanoparticles were loaded with the vesicles via in situ reduction, which can be used as a catalyst for the reduction of methylene blue (MB) in the presence of NaBH₄. Finally, gel permeation chromatography (GPC) analysis demonstrated that the corona block and the core-forming block could be cleaved by treating with excess initiator. This novel PISA formulation will greatly expand the scope of PISA and provide more mechanistic insights into the PISA research.

中文翻译：

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扩大聚合诱导自组装的范围：Z-RAFT 介导的光引发分散聚合

在本次交流中，我们开发了第一个基于丙烯酸叔丁酯 ( t BA)的光引发 RAFT 分散聚合的良好控制的 Z-RAFT (RAFT = 可逆加成-断裂链转移) 介导的聚合诱导自组装 (PISA) 配方在室温下使用 Z 型大分子链转移剂 (macro-CTA) 在乙醇/水 (60/40, w/w) 中。通过可见光照射（405 nm，0.45 mW/cm ²) 在 1 小时内实现高单体转化率 (>95%)。通过这种 Z-RAFT 介导的 PISA 配方制备了多种具有窄摩尔质量分布的聚合物纳米物体（球体、蠕虫和囊泡）。银纳米粒子通过原位还原负载囊泡，可用作在NaBH ₄存在下还原亚甲蓝（MB）的催化剂。最后，凝胶渗透色谱 (GPC) 分析表明，通过用过量引发剂处理，可以裂解电晕块和成芯块。这种新颖的 PISA 公式将极大地扩展 PISA 的范围，并为 PISA 研究提供更多的机制见解。