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Biphasic activation of complement and fibrinolysis during the human nasal allergic response
Journal of Allergy and Clinical Immunology ( IF 14.2 ) Pub Date : 2018-02-07 , DOI: 10.1016/j.jaci.2018.01.022
Ryan S Thwaites 1 , Natasha C Gunawardana 1 , Verena Broich 1 , Elizabeth H Mann 2 , Josefin Ahnström 3 , Gaynor A Campbell 1 , Sarah Lindsley 1 , Nehmat Singh 1 , Tanushree Tunstall 1 , David A Lane 3 , Peter J Openshaw 1 , Catherine M Hawrylowicz 2 , Trevor T Hansel 4
Affiliation  

Complement, coagulation and fibrinolysis contribute to the pathology of many respiratory diseases. Here we detail the biphasic activation of these pathways following nasal allergen challenge. Understanding these mechanisms may lead to therapeutic insight in common respiratory diseases.



中文翻译:

人鼻过敏反应过程中补体和纤溶的双相激活

补体、凝血和纤溶有助于许多呼吸系统疾病的病理学。在这里,我们详细介绍了鼻过敏原攻击后这些途径的双相激活。了解这些机制可能会导致对常见呼吸系统疾病的治疗洞察力。

更新日期:2018-02-08
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