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Limonene: Aroma of innovation in health and disease
Chemico-Biological Interactions ( IF 5.1 ) Pub Date : 2018-02-07
A.J. Vieira, F.P. Beserra, M.C. Souza, B.M. Totti, A.L. Rozza

Natural products obtained in dietary components may aid the prevention and treatment of a variety of diseases. Reports in the scientific literature have demonstrated that the consumption of terpenes is a successful alternative in the treatment of several diseases, triggering beneficial biological effects in clinical and preclinical studies. The monoterpene limonene is largely used in alimentary items, cleaning products, and it is one of the most frequent fragrances used in cosmetics formulation. The therapeutic effects of limonene have been extensively studied, proving anti-inflammatory, antioxidant, antinociceptive, anticancer, antidiabetic, antihyperalgesic, antiviral, and gastroprotective effects, among other beneficial effects in health. In this review, we collected, presented, and analyzed evidence from the scientific literature regarding the usage of limonene and its activities and underlying mechanisms involved in combating diseases. The highlighting of limonene applications could develop a useful targeting of innovative research in this field as well as the development of a limonene-based phytomedicine which could be used in a variety of conditions of health and disease.



中文翻译:

柠檬烯:健康和疾病方面的创新香气

从饮食成分中获得的天然产物可能有助于预防和治疗多种疾病。科学文献中的报告表明,食用萜烯是治疗多种疾病的成功替代方法,在临床和临床前研究中引发了有益的生物学作用。单萜烯mon烯广泛用于食品,清洁产品中,并且是化妆品配方中使用最频繁的香料之一。柠檬烯的治疗作用已被广泛研究,证明其具有消炎,抗氧化,抗伤害性,抗癌,抗糖尿病,抗痛觉过敏,抗病毒和胃保护作用,以及对健康有益的作用。在这篇评论中,我们收集,介绍了 并分析了科学文献中有关柠檬烯的使用及其活动以及与疾病抗争的潜在机制的证据。突出柠檬烯的应用可以开发该领域创新研究的有用目标,以及开发可以用于多种健康和疾病条件的基于柠檬烯的植物药。

更新日期:2018-02-08
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