当前位置: X-MOL 学术Meat Sci. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Association of single nucleotide polymorphisms in fat metabolism candidate genes with fatty acid profiles of muscle and subcutaneous fat in heavy pigs
Meat Science ( IF 7.1 ) Pub Date : 2018-02-07 , DOI: 10.1016/j.meatsci.2018.02.005
B. Renaville , N. Bacciu , M. Lanzoni , F. Mossa , E. Piasentier

Dietary and organoleptic qualities of pork products are largely influenced by the profiles of fatty acids (FAs) of meat and fat. The objective of this work was to investigate the potential associations between FA profile in subcutaneous adipose (back fat and leg fat) and muscular (longissimus dorsi and biceps femoris) tissues in heavy pigs (n = 129, 9-month-old) with single nucleotide polymorphisms (SNPs) in six candidate genes involved in fat metabolism: Stearoyl-CoA desaturase (SCD), Diacylglycerol acyltransferase 1 and 2 (DGAT1 & DGAT2), Microsomal Triglyceride Transfer Protein (MTTP), Fatty Acid Synthase (FASN) and Heart- fatty acid binding protein (H-FABP). Preliminary results suggest a putative association between MTTP, DGAT2 and FASN and the FA content in both fat and meat, whereas between DGAT1, SCD and H-FABP the association was found in adipose tissue only. However, the effect of the analyzed genes, needs to be verified in a larger and better characterized pig population to support the hypothesized associations with FA content.



中文翻译:

肥胖猪脂肪代谢候选基因中的单核苷酸多态性与肌肉和皮下脂肪的脂肪酸谱的关系

猪肉产品的饮食和感官品质在很大程度上受到肉和脂肪中脂肪酸(FAs)的影响。这项工作的目的是研究单只重猪(n = 129,9个月大)的皮下脂肪(背部脂肪和腿部脂肪)FA分布与肌肉组织(背最长肌股二头肌)之间的潜在关联。脂肪代谢涉及的六个候选基因中的核苷酸多态性(SNP):硬脂酰辅酶A去饱和酶(SCD),二酰基甘油酰基转移酶1和2(DGAT1DGAT2),微粒体甘油三酸酯转移蛋白(MTTP),脂肪酸合酶(FASN)和心脏脂肪酸结合蛋白(H- FABP)。初步结果表明,MTTPDGAT2FASN与脂肪和肉类中的FA含量之间存在推测的关联,而DGAT1SCDH-FABP之间的关联仅在脂肪组织中发现。但是,需要在更大,特征更好的猪群中验证所分析基因的作用,以支持与FA含量有关的假设关联。

更新日期:2018-02-07
down
wechat
bug