A visible light induced hydrodifluoromethylation of alkenes derived from oxindoles with (difluoromethyl)triphenylphosphonium bromide was developed. This reaction delivers a series of previously unknown difluoromethylated oxindoles containing CCF₂H quaternary centers in moderate to excellent yields. The resulting CF₂H-containing oxindoles are potentially useful in drug discovery.

中文翻译：

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可见光诱导与（二氟甲基）三苯基phosph溴化吲哚衍生的烯烃的加氢二氟甲基化

开发了可见光诱导的由（二氟甲基）三苯基phosph溴化物衍生自羟吲哚的烯烃的氢二氟甲基化。该反应以中等到极好的产率产生了一系列包含C CF ₂ H季中心的先前未知的二氟甲基化的吲哚。所得的含CF ₂ H的羟吲哚可能在药物发现中有用。