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Reprograming Immunity to Food Allergens
Journal of Allergy and Clinical Immunology ( IF 14.2 ) Pub Date : 2018-02-05 , DOI: 10.1016/j.jaci.2018.01.020 Ashley L. St John , W. X. Gladys Ang , Abhay P.S. Rathore , Soman N. Abraham
中文翻译:
重新编程对食物过敏原的免疫力
更新日期:2018-02-05
Journal of Allergy and Clinical Immunology ( IF 14.2 ) Pub Date : 2018-02-05 , DOI: 10.1016/j.jaci.2018.01.020 Ashley L. St John , W. X. Gladys Ang , Abhay P.S. Rathore , Soman N. Abraham
A novel immune-modulatory therapy utilizing targeted delivery of cytokines to draining lymph nodes effectively reprograms Th2 allergic responses towards a Th1 and tolerogenic profile, resulting in protection from peanut antigen-induced anaphylaxis.
中文翻译:
重新编程对食物过敏原的免疫力
一种新颖的免疫调节疗法,利用细胞因子靶向递送至引流淋巴结的方式有效地重编程针对Th1和致耐受性的Th2过敏反应,从而保护免受花生抗原诱导的过敏反应。