Abstract Eighteen extracts of six medicinal plants of Meru Betiri National Park (Jember, Indonesia) were studied for their anti-diabetic potency as well as their antioxidant activities (DPPH, superoxide anion and hydroxyl radical scavenging). Total phenolic and flavonoid content were also determined. Total phenols and flavonoid content increased with polarity order, from hexane, ethyl acetate to methanol extracts. Similar pattern resulted in antioxidant activity testing. Ethyl acetate extract of Antidesma bunius, methanol extract of Lagerstroemia speciosa and Lunasia amara possessed higher α-amilase inhibition compared to standard inhibitor, acarbose. Moreover, ethyl acetate extract of Antidesma bunius, methnaol extract of Arcangelisia flava, Lagerstroemia speciosa, Lunasia amara and hexane fraction of Merremia mamosa indicated higher α-glucosidase inhibition compared to standard anti-diabetic drug, acarbose. The extracts with higher phenolic and flavonoid content did not always showed higher inhibition activities α-amilase and α-glucosidase. Overall, the six medicinal plants exhibited potent sources for diabetic mellitus medication.

中文翻译：

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印度尼西亚任抹梅鲁贝蒂里国家公园药用植物的抗糖尿病功效

摘要 研究了 Meru Betiri 国家公园（印度尼西亚任抹）的六种药用植物的十八种提取物的抗糖尿病功效以及抗氧化活性（DPPH、超氧阴离子和清除羟基自由基）。还测定了总酚类和类黄酮含量。从己烷、乙酸乙酯到甲醇提取物，总酚和类黄酮含量随极性顺序增加。类似的模式导致抗氧化活性测试。Antidesma bunius 的乙酸乙酯提取物、Lagerstroemia speciosa 和 Lunasia amara 的甲醇提取物与标准抑制剂阿卡波糖相比具有更高的 α-淀粉酶抑制作用。此外，Antidesma bunius 的乙酸乙酯提取物、 Arcangelisia flava 的甲醇提取物、Lagerstroemia speciosa、与标准抗糖尿病药物阿卡波糖相比，Merremia mamosa 的 Lunasia amara 和己烷部分显示出更高的 α-葡萄糖苷酶抑制作用。酚类和类黄酮含量较高的提取物并不总是表现出较高的α-淀粉酶和α-葡萄糖苷酶抑制活性。总体而言，这六种药用植物显示出治疗糖尿病的有效来源。