The biological basis of consciousness is one of the most challenging and fundamental questions in 21st century science. A related pursuit aims to identify the neural correlates and causes of unconsciousness. We review current trends in the investigation of physiological, pharmacological, and pathological states of unconsciousness at the level of large-scale functional brain networks. We focus on the roles of brain connectivity, repertoire, graph-theoretical techniques, and neural dynamics in understanding the functional brain disconnections and reduced complexity that appear to characterize these states. Persistent questions in the field, such as distinguishing true correlates, linking neural scales, and understanding differential recovery patterns, are also addressed.

中文翻译：

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大规模脑网络中无意识的神经相关性

意识的生物学基础是 21 世纪科学中最具挑战性和基本的问题之一。一项相关的探索旨在确定无意识的神经相关因素和原因。我们回顾了在大规模功能性大脑网络水平上研究无意识的生理、药理学和病理状态的当前趋势。我们专注于大脑连接、曲目、图论技术和神经动力学在理解功能性大脑断开和似乎表征这些状态的复杂性降低方面的作用。还解决了该领域的持续问题，例如区分真正的相关性、连接神经尺度和理解差异恢复模式。