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Artificial Micro/Nanomachines for Bioapplications: Biochemical Delivery and Diagnostic Sensing
Advanced Functional Materials ( IF 19.0 ) Pub Date : 2018-02-02 , DOI: 10.1002/adfm.201705867
Kwanoh Kim 1, 2 , Jianhe Guo 3 , Zexi Liang 3 , Donglei Fan 1, 3
Affiliation  

Recent progress in artificial nanomachines offers promising solutions to grand challenges in biochemical delivery and diagnostics. In this work, advances of micro/nanomachines made of synthesized micro/nanostructures for applications in delivery and detection of biomolecules are reviewed, along with a discussion of pros and cons of each type of machine. The review of micro/nanomachines is categorized according to their working mechanisms, including motion actuation realized by magnetic, electric, and acoustic fields and chemical reactions. The developments of micro/nanomachines are discussed in depth in the fabrication, propulsion, and motion control, loading and releasing of micro/nanosubstances, and biochemical sensing. The rapid development of man‐made miniaturized machines paves the road toward future intelligent nanorobots and nanofactories that can revolutionize society.

中文翻译:

用于生物应用的人造微型/纳米机器:生化传递和诊断传感

人工纳米机器的最新进展为生物化学传递和诊断方面的巨大挑战提供了有希望的解决方案。在这项工作中,综述了由合成的微/纳米结构制成的微/纳米机器在生物分子的传递和检测中的应用,并讨论了每种机器的优缺点。微型/纳米机械设备按其工作机制分类,包括通过磁场,电场和声场以及化学反应实现的运动致动。微型/纳米机器的发展在制造,推进和运动控制,微型/纳米物质的装载和释放以及生化感测方面进行了深入讨论。
更新日期:2018-02-02
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