Acceptability of medicinal products in children and older populations is pivotal in ensuring adherence and therapeutic outcomes. This review systematically identifies studies reporting on formulation aspects of oral medications that affect their acceptability in these patient groups. Particular emphasis is placed on the evaluation of the methodologies employed in the studies. Sixty-eight studies were included for analysis, with 51 (75%) in children and 17 (25%) in older populations. The studies evaluated a range of oral formulations; however, the methodologies used differ considerably in participants’ characteristics, study settings, tools, acceptability definitions and criteria. It is evident that there is a lack of standardisation in study design as well as the assessment methods used in assessing acceptability of medicines in children and older populations.

儿童和老年人口中药用产品的可接受性对于确保依从性和治疗效果至关重要。这篇综述系统地鉴定了报告口服药物制剂方面的研究，这些方面影响了口服药物在这些患者组中的可接受性。特别强调对研究中使用的方法学的评估。包括68项研究进行分析，其中51项（75％）用于儿童，17项（25％）用于老年人。研究评估了一系列口服制剂。但是，所使用的方法在参与者的特征，研究设置，工具，可接受性定义和标准方面存在很大差异。