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Histone Methyltransferase Setd7 Regulates Nrf2 Signaling Pathway by Phenethyl Isothiocyanate and Ursolic Acid in Human Prostate Cancer Cells
Molecular Nutrition & Food Research ( IF 5.2 ) Pub Date : 2018-03-06 , DOI: 10.1002/mnfr.201700840
Chao Wang 1, 2 , Limin Shu 1, 2 , Chengyue Zhang 1, 2 , Wenji Li 1, 2 , Renyi Wu 1, 2 , Yue Guo 1, 2 , Yuqing Yang 1, 2 , Ah-Ng Kong 1, 2
Affiliation  

This study aims to investigate the role of the epigenetic regulator SET domain‐containing lysine methyltransferase 7 (Setd7) in regulating the antioxidant Nrf2 pathway in prostate cancer (PCa) cells and examines the effects of two phytochemicals, phenethyl isothiocyanate (PEITC) and ursolic acid (UA).

中文翻译:

组蛋白甲基转移酶Setd7调节人前列腺癌细胞中异硫氰酸苯乙酯和熊果酸的Nrf2信号通路。

这项研究旨在探讨表观遗传调控因子SET结构域中含有赖氨酸甲基转移酶7(Setd7)在调控前列腺癌(PCa)细胞抗氧化剂Nrf2途径中的作用,并研究两种植物化学物质异硫氰酸苯乙酯(PEITC)和熊果酸的作用。 (UA)。
更新日期:2018-03-06
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