We first applied the genome edited silkworm silk (GE-silk) to interpret X-ray fiber diagram, and implied a great potential for the application of genome editing technology to the structural study of silk. The origin of a weak meridional layer-line streak with a spacing of ∼21 Å, observed in the X-ray fiber diagram of Bombyx mori silkworm silk, has been widely believed but not experimentally proven to be a period of the pseudostructure associated with the occurrence of serine residues at regular intervals in a hexapeptide repeating unit -G-A-G-A-G-S-. The above hypothesis was experimentally demonstrated from X-ray measurements of GE-silk.

中文翻译：

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基因组编辑促进了丝绸的结构研究

我们首先应用基因组编辑的蚕丝（GE-silk）来解释X射线纤维图，这暗示了将基因组编辑技术应用到蚕丝的结构研究中的巨大潜力。在家蚕的X射线纤维图中观察到的间距为21Å的弱子午线层状条纹的起源已被广泛认为，但未经实验证明是与之相关的伪结构时期。六肽重复单元-GAGAGS-中定期出现丝氨酸残基。以上假设是通过GE丝绸的X射线测量实验证明的。