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Functional amyloid materials at surfaces/interfaces
Biomaterials Science ( IF 6.6 ) Pub Date : 2018-01-30 00:00:00 , DOI: 10.1039/c7bm01124e
Chen Li 1, 2, 3, 4, 5 , Rongrong Qin 1, 2, 3, 4, 5 , Ruirui Liu 1, 2, 3, 4, 5 , Shuting Miao 1, 2, 3, 4, 5 , Peng Yang 1, 2, 3, 4, 5
Affiliation  

With the development of nanotechnology, functional amyloid materials are drawing increasing attention, and numerous remarkable applications are emerging. Amyloids, defined as a class of supramolecular assemblies of misfolded proteins or peptides into β-sheet fibrils, have evolved in many new respects and offer abundant chemical/biological functions. These proteinaceous micro/nano-structures provide excellent biocompatibility, rich phase behaviours, strong mechanical properties, and stability at interfaces not only in nature but also in functional materials, displaying versatile interactions with surfaces/interfaces that have been widely adopted in bioadhesion, synthetic biology, and composites. Overall, functional amyloids at surfaces/interfaces have excellent potential applications in next-generation biotechnology and biomaterials.

中文翻译:

表面/界面处的功能淀粉样物质

随着纳米技术的发展,功能性淀粉样物质越来越受到关注,并且出现了许多引人注目的应用。淀粉样蛋白定义为将错误折叠的蛋白质或肽折叠成β-片状原纤维的一类超分子组装,它在许多新方面得到了发展,并提供了丰富的化学/生物学功能。这些蛋白质的微/纳米结构不仅在自然界而且在功能性材料中均具有出色的生物相容性,丰富的相行为,强大的机械性能以及在界面处的稳定性,显示出与已在生物粘附,合成生物学中广泛采用的表面/界面的多种相互作用。 ,以及复合材料。总体而言,表面/界面上的功能淀粉样蛋白在下一代生物技术和生物材料中具有极好的潜在应用。
更新日期:2018-01-30
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