Cocaine-associated environmental cues can precipitate craving and relapse in addicted individuals even after years of abstinence, but the molecular mechanisms by which maladaptive drug memories are generated remain unclear. New findings suggest that histone deacetylase 5 (HDAC5) plays a key role in this process.

中文翻译：

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HDAC5调节药物记忆的形成

可卡因相关的环境线索即使在戒酒多年后仍可能使成瘾的个体渴望和复发，但是产生不良适应性药物记忆的分子机制仍不清楚。新发现表明，组蛋白脱乙酰基酶5（HDAC5）在此过程中起关键作用。