Mass spectrometry: Raw protein from the top down

Mass spectrometry: Raw protein from the top down, Published online: 23 January 2018; doi:10.1038/nchem.2936

Mass spectrometry is a powerful technique for analysing proteins, yet linking higher-order protein structure to amino acid sequence and post-translational modifications is far from simple. Now, a native top-down method has been developed that can provide information on higher-order protein structure and different proteoforms at the same time.

中文翻译：

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质谱：自上而下的原始蛋白质

质谱：自上而下的原始蛋白质

质谱：自上而下的原始蛋白质，在线发布：2018年1月23日; doi：10.1038 / nchem.2936

质谱分析是一种用于分析蛋白质的强大技术，但是将高级蛋白质结构与氨基酸序列和翻译后修饰联系起来远非简单易行。现在，已经开发出一种自然的自上而下的方法，该方法可以同时提供有关高阶蛋白质结构和不同蛋白形式的信息。