We present a novel metal-ion stimulated organization of DNA origami nanostructures by employing G-quadruplexes as stimuli-responsive bridges. The reversible assembly process of DNA origami was the result of conformational changes between the G-quadruplex and its single-strand state induced by monovalent cations. This study might stimulate a new design of responsive DNA-based intelligent nanomaterials.

中文翻译：

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DNA折纸二聚体的金属离子反应性可逆组装：G-四链体诱导的分子间相互作用†

我们通过使用G-四链体作为刺激响应桥，提出了一种新颖的金属离子刺激的DNA折纸纳米结构的组织。DNA折纸的可逆组装过程是G四链体与单价阳离子诱导的单链状态之间构象变化的结果。这项研究可能会刺激基于响应DNA的智能纳米材料的新设计。