The rhodium-catalyzed asymmetric N¹-selective and regioselective coupling of triazole derivatives with internal alkynes and terminal allenes gives access to secondary and tertiary allylic triazoles in very good enantioselectivities. For this process, three new members of the JosPOphos ligand family have been prepared and employed in catalysis. The optimized reaction conditions enable the coupling of triazoles with internal alkynes as well as with allenes, displaying a high tolerance for functional groups. A gram scale reaction provided N¹-allyltriazole, which was subjected to various transformations highlighting synthetic utility.

中文翻译：

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三唑与内部炔烃和末端亚烯基的化学，区域和对映体选择性催化的铑催化的烯丙基化

三唑衍生物与内部炔烃和末端异戊烯的铑催化的不对称N ¹选择性和区域选择性偶合使仲和叔烯丙基三唑具有很好的对映选择性。对于此过程，已制备了JosPOphos配体家族的三个新成员并将其用于催化。优化的反应条件能够使三唑与内部炔烃和丙二烯偶联，显示出对官能团的高耐受性。克级反应提供了N ^1-烯丙基三唑，将其进行了各种转化，突出了合成用途。