The ankle-brachial index (ABI) is a reliable diagnostic examination for peripheral arterial occlusive disease (PAOD). We previously reported CHADS₂ score was significantly correlated with PAOD. However, the association between CHA₂DS₂-VASc score and ABI < 0.9 is not evaluated in the literature. The aim of the present study was to investigate whether CHA₂DS₂-VASc score has a strong association with PAOD. We enrolled 1482 patients in this study. PAOD was defined as ABI < 0.9 in either leg. Vascular disease in CHA₂DS₂-VASc score was modified as vascular disease except PAOD. Of the 1482 subjects, the prevalence of ABI < 0.9 was 5.6%. Multivariate analysis showed that the increased age, decreased estimated glomerular filtration rate and increased modified CHA₂DS₂-VASc score (OR, 1.764; p < 0.001) were independent associated with ABI < 0.9. In addition, the percentage of ABI < 0.9 in patients with modified CHA₂DS₂-VASc score of 0, 1, and <2 were 0%, 0.9%, and 0.7%, respectively (All < 1%). Our study demonstrated modified CHA₂DS₂-VASc score was significantly associated with ABI < 0.9. Calculation of modified CHA₂DS₂-VASc score might be useful in identifying patients with PAOD and in stratifying the risk of PAOD in non-AF patients.

中文翻译：

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修正的CHA2DS2-VASc评分与踝肱指数<0.9之间的关联。

踝臂指数（ABI）是对外周动脉闭塞性疾病（PAOD）的可靠诊断检查。我们先前曾报道CHADS ₂评分与PAOD显着相关。但是，文献中未评估CHA ₂ DS ₂ -VASc评分与ABI <0.9之间的关联。本研究的目的是调查CHA ₂ DS ₂ -VASc评分是否与PAOD密切相关。我们在这项研究中招募了1482名患者。两条腿的PAOD定义为ABI <0.9。CHA ₂ DS _2中的血管疾病-VASc评分被修改为除PAOD以外的血管疾病。在1482名受试者中，ABI <0.9的患病率为5.6％。多变量分析显示，年龄的增加，肾小球滤过率的降低和改良的CHA ₂ DS ₂ -VASc评分的增加（OR，1.764； p <0.001）与ABI <0.9无关。此外，CHA ₂ DS ₂ -VASc评分修改为0、1和<2的患者中ABI <0.9的百分比分别为0％，0.9％和0.7％（全部<1％）。我们的研究表明，改良的CHA ₂ DS ₂ -VASc评分与ABI <0.9显着相关。修改后的CHA ₂ DS _2的计算-VASc评分可能有助于识别患有PAOD的患者以及对非AF患者的PAOD风险进行分层。