Breast size as a risk factor of breast cancer has been studied extensively with inconclusive results. Here we examined the associations between breast size and breast cancer risk factors in 24,353 Asian women aged 50 to 64 years old enrolled in a nationwide mammography screening project conducted between October 1994 and February 1997. Information on demographic and reproductive factors was obtained via a questionnaire. Breast size was ascertained as bust line measured at study recruitment and total breast area measured from a mammogram. The average bust line and total breast area was 91.2 cm and 102.3 cm², respectively. The two breast measurements were moderately correlated (Spearman correlation coefficient = 0.65). Age, BMI, marital and working status were independently associated with bust line and total breast area. In the multivariable analyses, the most pronounced effects were observed for BMI (24.2 cm difference in bust line and 39.4 cm² in breast area comparing women with BMI ≥30 kg/m² to BMI <20 kg/m²). Ethnicity was a positive predictor for total breast area, but not bust line.

中文翻译：

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亚洲女性乳房大小的决定因素。

乳房尺寸作为乳腺癌的危险因素已被广泛研究，但结论尚无定论。在这里，我们研究了1994年10月至1997年2月在全国进行的X线钼靶筛查项目中纳入的24,353名年龄在50至64岁之间的亚裔女性中，乳腺癌的大小与乳腺癌危险因素之间的关系。确定乳房大小，作为在研究募集时测量的胸围和从乳房X线照片测量的总乳房面积。平均胸围和乳房总面积分别为91.2 cm和102.3 cm ²， 分别。两次乳房测量值具有中等相关性（Spearman相关系数= 0.65）。年龄，BMI，婚姻状况和工作状态与胸围和乳房总面积独立相关。在多变量分析中，观察到对于BMI的最显着的效应（在胸围线24.2厘米差和39.4厘米²在乳房区域进行比较妇女与BMI≥30公斤/米²至BMI <为20kg /米²）。种族是乳房总面积的积极预测指标，但对胸围却不是。