We appreciated the comments by Ugarte-Gil and co-authors1 on our report dealing with lupus low disease activity state (LLDAS) in Caucasian patients.2 We agree that Caucasian patients with systemic lupus erythematosus (SLE) have a better prognosis compared with non-Caucasian ones, but, in our opinion, race does not fully elucidate the different results in terms of prevalence of low disease activity and remission obtained in the studies by Zen et al 2 and Ugarte-Gil et al .3 The different design of the studies is more relevant than race in explaining the divergent results. Indeed, the Grupo Latino Americano De Estudio del Lupus (GLADEL) study3 analysed an inception cohort of patients shortly after the disease onset (median disease duration 0.3 years), and the authors assessed remission and low disease activity status (LDAS) during the first years of follow-up. …

中文翻译：

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回应：Ugarte-Gilet al 将“缓解或低疾病活动度作为系统性红斑狼疮的目标”

我们感谢 Ugarte-Gil 和合著者 1 对我们关于白人患者狼疮低度疾​​病活动状态 (LLDAS) 的报告的评论。2 我们同意，与非系统性红斑狼疮 (SLE) 白人患者相比，患有系统性红斑狼疮 (SLE) 的白人患者预后更好。白种人，但在我们看来，种族并没有完全阐明 Zen 等人 2 和 Ugarte-Gil 等人 3 研究中获得的低疾病活动性和缓解流行率方面的不同结果。 研究的不同设计在解释不同的结果时，比种族更相关。事实上，Grupo Latino Americano De Estudio del Lupus (GLADEL) 研究 3 分析了疾病发作后不久的患者队列（中位疾病持续时间为 0.3 年），作者在随访的头几年评估了缓解和低疾病活动状态 (LDAS)。…