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Engineering precision biomaterials for personalized medicine
Science Translational Medicine ( IF 17.1 ) Pub Date : 2018-01-17 , DOI: 10.1126/scitranslmed.aam8645
Brian A Aguado 1, 2, 3 , Joseph C Grim 1, 2, 3 , Adrianne M Rosales 1, 2 , Jana J Watson-Capps 2 , Kristi S Anseth 1, 2, 3
Affiliation  

As the demand for precision medicine continues to rise, the “one-size-fits-all” approach to designing medical devices and therapies is becoming increasingly outdated. Biomaterials have considerable potential for transforming precision medicine, but individual patient complexity often necessitates integrating multiple functions into a single device to successfully tailor personalized therapies. Here, we introduce an engineering strategy based on unit operations to provide a unified vocabulary and contextual framework to aid the design of biomaterial-based devices and accelerate their translation.



中文翻译:

用于个性化医疗的工程精密生物材料

随着精准医疗需求的持续增长,“一刀切”的医疗设备和疗法设计方法正变得越来越过时。生物材料在改变精准医疗方面具有巨大潜力,但个体患者的复杂性通常需要将多种功能集成到单个设备中,以成功定制个性化治疗。在这里,我们引入了一种基于单元操作的工程策略,以提供统一的词汇和上下文框架,以帮助基于生物材料的设备的设计并加速其翻译。

更新日期:2018-01-18
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