The cell surface serves important functions such as the regulation of cell‐cell and cell‐environment interactions. The understanding and manipulation of the cell surface is important for a wide range of fundamental studies of cellular behavior and for biotechnological and medical applications. With the rapid advance of biology, chemistry and materials science, many strategies have been developed for the functionalization of bacterial and mammalian cell surfaces. Here, we review the recent development of chemical and enzymatic approaches to cell surface engineering with particular emphasis on discussing the advantages and limitations of each of these strategies.

中文翻译：

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细菌和哺乳动物细胞表面工程的化学和酶促策略

细胞表面起着重要的功能，例如调节细胞间和细胞与环境之间的相互作用。细胞表面的理解和操纵对于细胞行为的广泛基础研究以及生物技术和医学应用非常重要。随着生物学，化学和材料科学的飞速发展，已经开发了许多用于细菌和哺乳动物细胞表面功能化的策略。在这里，我们回顾了化学和酶促方法对细胞表面工程的最新发展，特别着重讨论了每种策略的优势和局限性。