The process of obtaining the composite layer consisting of conductive copolymer, composed of unmodified pyrrole and pyrrole-3-carboxylic acid units (in various molar ratio) in combination with magnetic nanoparticles was investigated using voltammetry, scanning electron microscopy, transmission electron microscopy, scanning transmission electron microscopy and surface enhanced Raman scattering (SERS) spectroscopy. The SERS and voltammetric data demonstrate that the use of molar concentration ratio of monomers 75 (Py) to 25 mM (Py-COOH) results in the conductive polymer layer with the best bioelectrochemical properties. The ferritin attached covalently to such composite demonstrated the highest electroactivity. Thus, mixed conductive copolymer film containing Py and Py-COOH units, combined with magnetic nanoparticles could be further useful in developing bioactive conductive platforms for specific biomedical purposes.

使用伏安法，扫描电子显微镜，透射电子显微镜，扫描透射法研究了由导电共聚物组成的复合层的过程，该复合层由未改性的吡咯和吡咯-3-羧酸单元（不同摩尔比）与磁性纳米粒子组合而成电子显微镜和表面增强拉曼散射（SERS）光谱。SERS和伏安数据表明，单体75（Py）与25 mM（Py-COOH）的摩尔浓度比的使用可产生具有最佳生物电化学性能的导电聚合物层。共价附于这种复合物的铁蛋白显示出最高的电活性。因此，包含Py和Py-COOH单元的混合导电共聚物膜