In this article, we examine the status of the National Institutes of Health (NIH) pediatric research portfolio between start of federal fiscal year (FY) 1992 and end of FY 2015. The NIH experienced the greatest mean annual growth rate during the “doubling era” (FY 1998-2003): both the NIH budget (13.5%) and pediatric research portfolios (11.5%) increased annually by double digits. However, in the “postdoubling” era (FY 2004-2009), both the NIH (2.0%) and pediatric (−0.2%) mean annual growth rates decreased dramatically. In the most recent era (FY 2010-2015), the NIH mean annual growth rate has been flat (−0.1%) and pediatric research funding has posted very modest gains (3.5%) without accounting for 1-time increases under the 2009 American Recovery and Reinvestment Act. We offer recommendations to protect against further erosion of the pediatric research portfolio because continuation of these trends will have a negative effect on the health of children during their childhood and as adults. As capacity to conduct basic and applied research is further constrained, it will be a challenge for pediatric researchers to do more with less and less.

中文翻译：

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美国国立卫生研究院儿科研究组合的脆弱状态，1992-2015

在本文中，我们检查了 1992 年联邦财政年度 (FY) 开始和 2015 财政年度结束之间美国国立卫生研究院 (NIH) 儿科研究组合的状况。 NIH 在“翻倍时代”经历了最大的平均年增长率”（1998-2003 财年）：NIH 预算（13.5%）和儿科研究组合（11.5%）每年都以两位数的速度增长。然而，在“后倍增”时代（2004-2009 财年），NIH (2.0%) 和儿科 (-0.2%) 的年均增长率急剧下降。在最近的一个时代（2010-2015 财年），NIH 平均年增长率持平（-0.1%），儿科研究资金的增长非常温和（3.5%），而没有考虑到 2009 年美国复苏和再投资法案。我们提供建议以防止儿科研究组合进一步受到侵蚀，因为这些趋势的持续将对儿童在童年和成年期间的健康产生负面影响。由于开展基础和应用研究的能力进一步受到限制，儿科研究人员以更少的资源做更多的事情将是一个挑战。