The IL-1 family of cytokines follows an unconventional pathway of secretion mostly associated with inflammatory cell death. In this issue of Immunity, (Evavold et al., 2017) report gasdermin D pores as channels for active IL-1 release in live phagocytic cells.

中文翻译：

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加德明D闪烁IL-1的退出信号

IL-1家族的细胞因子遵循非常规的分泌途径，通常与炎性细胞死亡有关。在本期《免疫》（Evavold等人，2017）中，加德明D毛孔是活吞噬细胞中主动IL-1释放的通道。