当前位置: X-MOL 学术ChemBioChem › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Investigating Nucleosome Accessibility for MNase, FeII Peplomycin, and Duocarmycin B2 by Using Capillary Electrophoresis
ChemBioChem ( IF 3.2 ) Pub Date : 2018-02-12 , DOI: 10.1002/cbic.201700643
Tingting Zou 1 , Seiichiro Kizaki 1 , Hiroshi Sugiyama 1, 2
Affiliation  

Accessibility for all: MNase exhibited enhanced reactivity in the nucleosome and selectively cleaved DNA sites near the core region, whereas FeII‐peplomycin was highly suppressed for approaching the nucleosomal core region but was still able to react with the flexible core DNA end.
image


中文翻译:

使用毛细管电泳研究MNase,FeII霉素和Duocarmycin B2的核小体可及性

人人可接近:MNase在核小体中显示出增强的反应性,并选择性地切割了核心区域附近的DNA位点,而Fe II-聚霉素被高度抑制接近核小体核心区域,但仍能够与柔性核心DNA末端反应。
图像
更新日期:2018-02-12
down
wechat
bug