The induction of brown‐like adipocytes in white adipose tissue (WAT) is a potential therapeutic target for the treatment of obesity and metabolic disorders via the ability of these cells to release excess energy as heat in association with uncoupling protein 1. Some experimental trials suggest that curcumin (a yellow pigment from turmeric) has a suppressive effect on the accumulation of body fat. However, there is little evidence to show that curcumin induces the formation of brown‐like adipocytes and the molecular mechanisms involved remain elusive. In addition, in most experimental trials, high doses of curcumin are administered.

中文翻译：

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姜黄素具有高度分散性和生物利用性，但天然姜黄素不具有诱导小鼠棕色脂肪细胞形成的作用

白色脂肪组织（WAT）中褐色样脂肪细胞的诱导是肥胖和代谢性疾病的潜在治疗靶标，因为这些细胞具有释放热量的能力，并与解偶联蛋白1相关联。姜黄素（姜黄的黄色颜料）对体内脂肪的积累具有抑制作用。但是，几乎没有证据表明姜黄素能诱导褐色脂肪细胞的形成，并且涉及的分子机制仍然难以捉摸。另外，在大多数实验性试验中，都施用高剂量的姜黄素。