A convergent total synthesis of (−)-dactylolide is described. Constructing the 2,6-disubstituted exo-methylene THP moiety was achieved by the intramolecular allylation of α-acetoxy ether. The cyclization precursor was prepared from two segments, an alcohol and carboxylic acid derivatives, by esterification followed by reductive acetylation.

中文翻译：

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（-）-半乳糖苷的聚合全合成

描述了（-）-癸二酰肼的会聚全合成。通过α-乙酰氧基醚的分子内烯丙基化来构建2，6-二取代的外-亚甲基THP部分。环化前体由两个部分（醇和羧酸衍生物）制备，先进行酯化反应，然后进行还原性乙酰化反应。