Nanotechnology has been widely used for developing sensors with higher sensitivity and better selectivity. In this study, a molecularly imprinted electrochemical sensor based on nitrogen-doped carbon nanosheet frameworks decorated with Fe (Fe-NCNF) was proposed for simultaneous detection of mebendazole (Meb) and catechol (CC). Fe-NCNF was prepared by chemical blowing, and it was coated with molecularly imprinted polymer (MIP) to construct a novel hybrid nanomaterial, which is named Fe-NCNF/MIP. Meb-MIP was electropolymerized with methacrylic acid (MAA) as monomer via cyclic voltammetry (CV) method. This sensor architecture can detect Meb because of the high binding affinity of MIP. With the large specific surface area, Fe-NCNF can adsorb and electrochemically oxidize CC. The good selectivity of Fe-NCNF/MIP for CC and Meb was proven by anti-interference test, for which the oxidation potentials were set at 0.15 and 0.82 V respectively. The linear range for determination of CC was from 0.5 to 25 μM with a low limit of detection (LOD) of 0.06 μM (S/N = 3), and that for Meb was 0.01–1.5 μM with a low LOD of 0.004 μM (S/N = 3). Furthermore, this MIP electrochemical sensor was applied for the simultaneous detection of CC and Meb in tap water and river water. These results demonstrated that this method is reliable for selective, sensitive and feasible determination of Meb and CC.

纳米技术已被广泛用于开发具有更高灵敏度和更好选择性的传感器。在这项研究中，提出了一种分子印迹电化学传感器，该传感器基于掺有Fe的氮掺杂碳纳米片框架（Fe-NCNF），用于同时检测甲苯达唑（Meb）和邻苯二酚（CC）。通过化学吹塑法制备Fe-NCNF，并在其上涂覆分子印迹聚合物（MIP），以构建新型的杂化纳米材料，称为Fe-NCNF / MIP。通过循环伏安法（CV）将Meb-MIP与甲基丙烯酸（MAA）作为单体进行电聚合。由于MIP具有很高的结合亲和力，因此该传感器体系结构可以检测Meb。Fe-NCNF具有较大的比表面积，可以吸附和电化学氧化CC。通过抗干扰试验证明了Fe-NCNF / MIP对CC和Meb的良好选择性，其氧化电位分别设置为0.15和0.82V。测定CC的线性范围为0.5至25μM，检测下限（LOD）为0.06μM（S / N = 3），而Meb的线性范围为0.01–1.5μM，低LOD为0.004μM（ S / N = 3）。此外，该MIP电化学传感器还用于同时检测自来水和河水中的CC和Meb。这些结果表明，该方法对于选择性，灵敏和可行的Meb和CC测定是可靠的。5μM，低LOD为0.004μM（S / N = 3）。此外，该MIP电化学传感器还用于同时检测自来水和河水中的CC和Meb。这些结果表明，该方法对于选择性，灵敏和可行的Meb和CC测定是可靠的。5μM，低LOD为0.004μM（S / N = 3）。此外，该MIP电化学传感器还用于同时检测自来水和河水中的CC和Meb。这些结果表明，该方法对于选择性，灵敏和可行的Meb和CC测定是可靠的。