Previous experiments observed auto‐acceleration in the etherification of glycerol with isobutene. This article engaged to uncover the reason for this phenomenon via investigating the heterogenicity, including liquid–liquid phase equilibrium and liquid–liquid–solid mass transfer, of the reaction system. Phase behavior analysis showed that the reaction mixture separates into two liquid phases during the whole course of the reaction. The produced mono ethers of glycerol thermodynamically promote the homogenization of the two liquid phases. The modeling results of liquid–liquid–solid mass transfer indicated that the resistance of mass transfer is insignificant during the reaction. The bulk compositions of the two liquid phases are very close to their corresponding equilibrium compositions. An increase of isobutene concentration in the reaction phase is believed to lead all reactions speeding up. © 2018 American Institute of Chemical Engineers AIChE J, 64: 2526–2535, 2018

中文翻译：

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甘油与异丁烯的液-液-固传质及相行为

先前的实验观察到甘油与异丁烯的醚化反应会自动加速。本文致力于通过研究反应系统的异质性（包括液相-液相平衡和液-液-固传质）来发现这种现象的原因。相行为分析表明，在整个反应过程中，反应混合物分成两个液相。产生的甘油单醚在热力学上促进了两个液相的均质化。液-液-固传质的模拟结果表明，在反应过程中传质阻力微不足道。两种液相的本体组成非常接近其相应的平衡组成。据信反应相中异丁烯浓度的增加导致所有反应加速。©2018美国化学工程师学会AIChE J，64：2526–2535，2018年