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RNA‐Templated Concatenation of Triplet Nucleic‐Acid Probe
ChemBioChem ( IF 3.2 ) Pub Date : 2018-02-12 , DOI: 10.1002/cbic.201700574
Raman Bahal 1 , Arunava Manna 2 , Wei-Che Hsieh 2 , Shivaji A Thadke 2 , Gopalsamy Sureshkumar 2 , Danith H Ly 2
Affiliation  

RNA‐templated concatenation: A trinucleotide γ‐peptide nucleic acid containing a C‐terminal thioester and an N‐terminal cystine undergoes RNA‐templated concatenation upon reduction of the disulfide bond and self‐deactivation (intramolecular cyclization) in the absence of an RNA target. MPγPNA=miniPEG‐γ‐peptide nucleic acid.
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中文翻译:

三联体核酸探针的 RNA 模板串联

RNA 模板连接:含有 C 末端硫酯和 N 末端胱氨酸的三核苷酸 γ 肽核酸在没有 RNA 靶标的情况下,在二硫键还原和自失活(分子内环化)时进行 RNA 模板连接. MPγPNA=miniPEG-γ-肽核酸。
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更新日期:2018-02-12
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