当前位置: X-MOL 学术Eur. Respir. J. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Balloon pulmonary angioplasty in sarcoid-related pulmonary hypertension
European Respiratory Journal ( IF 24.3 ) Pub Date : 2018-01-01 , DOI: 10.1183/13993003.01502-2017
Jelco Tramper , Esther J. Nossent , Rutger J. Lely , Frans H. Krouwels , Lilian J. Meijboom , Anton Vonk Noordegraaf

A 43-year-old, never-smoking, African-American female was referred to our outpatient clinic for progressive dyspnoea. She had a medical history of sarcoidosis with lymph-node, pulmonary, skin and ocular involvement. Diagnosis was based on a previously conducted chest high-resolution computed tomography (CT) that showed bilateral hilar and mediastinal lymphadenopathy containing calcifications and multiple small lung nodules with peri-lymphatic distribution along the pleura and fissures A histological analysis of biopsy specimens from a lymph node located in the left side of the neck revealed large granulomas with multinucleated foreign body giant cells without necrosis. Microbiological cultures were negative. Extrapulmonary manifestations consisted of anterior uveitis and several cutaneous lesions and the reason for initiating corticosteroid therapy, which ameliorated the sarcoidosis. After discontinuation of corticosteroid therapy, the patient's condition deteriorated and she developed progressive dyspnoea (New York Heart Association (NYHA) functional class 3). Thoracic CT showed bilateral pleural and pericardial effusion. There were no signs of pulmonary fibrosis or cardial signs of pulmonary hypertension (PH). Analysis of the pleural fluid showed exudation with lymphocytosis. An infectious cause was excluded. Balloon pulmonary angioplasty can be a successful treatment option in pulmonary hypertension due to sarcoidosis http://ow.ly/ul4w30h4GVW

中文翻译:

结节相关性肺动脉高压的球囊肺血管成形术

一名 43 岁、从不吸烟的非裔美国女性因进行性呼吸困难被转诊至我们的门诊。她有结节病病史,淋巴结、肺、皮肤和眼部受累。诊断基于先前进行的胸部高分辨率计算机断层扫描 (CT),显示双侧肺门和纵隔淋巴结肿大,包含钙化和多个小肺结节,沿胸膜和裂隙分布在淋巴周围 淋巴结活检标本的组织学分析位于颈部左侧,可见大肉芽肿,多核异物巨细胞,无坏死。微生物培养阴性。肺外表现包括前葡萄膜炎和几个皮肤病变以及开始皮质类固醇治疗的原因,从而改善了结节病。停止皮质类固醇治疗后,患者病情恶化,出现进行性呼吸困难(纽约心脏协会 (NYHA) 功能等级 3)。胸部CT显示双侧胸腔和心包积液。没有肺纤维化的迹象或肺动脉高压 (PH) 的心脏迹象。胸水分析显示有淋巴细胞增多的渗出。排除感染原因。球囊肺血管成形术可以成为结节病引起的肺动脉高压的成功治疗选择 http://ow.ly/ul4w30h4GVW s 病情恶化,她出现进行性呼吸困难(纽约心脏协会 (NYHA) 功能等级 3)。胸部CT显示双侧胸腔和心包积液。没有肺纤维化的迹象或肺动脉高压 (PH) 的心脏迹象。胸水分析显示有淋巴细胞增多的渗出。排除感染原因。球囊肺血管成形术可以成为结节病引起的肺动脉高压的成功治疗选择 http://ow.ly/ul4w30h4GVW s 病情恶化,她出现进行性呼吸困难(纽约心脏协会 (NYHA) 功能等级 3)。胸部CT显示双侧胸腔和心包积液。没有肺纤维化的迹象或肺动脉高压 (PH) 的心脏迹象。胸水分析显示有淋巴细胞增多的渗出。排除感染原因。球囊肺血管成形术可以成为结节病引起的肺动脉高压的成功治疗选择 http://ow.ly/ul4w30h4GVW 排除感染原因。球囊肺血管成形术可以成为结节病引起的肺动脉高压的成功治疗选择 http://ow.ly/ul4w30h4GVW 排除感染原因。球囊肺血管成形术可以成为结节病引起的肺动脉高压的成功治疗选择 http://ow.ly/ul4w30h4GVW
更新日期:2018-01-01
down
wechat
bug