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Asymmetric Catalytic Preparation of Polysubstituted Cyclopropanol and Cyclopropylamine Derivatives
Angewandte Chemie International Edition ( IF 16.6 ) Pub Date : 2018-01-10 , DOI: 10.1002/anie.201710707
Marwan Simaan 1 , Ilan Marek 1
Affiliation  

The catalytic asymmetric carbometalation of cyclopropenes followed by either an electrophilic oxidation or amination reaction provides a unique approach to the formation of diastereomerically pure and enantiomerically enriched cyclopropanol and cyclopropylamine derivatives, respectively.

中文翻译:

多取代环丙醇和环丙胺衍生物的不对称催化制备

环丙烯的催化不对称碳金属化,然后进行亲电氧化或胺化反应,为形成非对映体纯和对映体富集的环丙醇和环丙胺衍生物提供了独特的方法。
更新日期:2018-01-10
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