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Domino Reaction of Naphthoquinone and β‐Arylpyruvic Acids: Synthesis of 3‐(Naphthoquinonyl)naphthofuran‐2(3H)‐ones
European Journal of Organic Chemistry ( IF 2.8 ) Pub Date : 2018-02-28 , DOI: 10.1002/ejoc.201701656
Laura Ortiz-Rojano 1 , Mario Martínez-Mingo 1 , Carolina García-García 1 , María Ribagorda 1, 2 , M. Carmen Carreño 1, 2
Affiliation  

β‐Arylpyruvic acid derivatives display dual reactivity upon reaction with naphthoquinone, initially by acting as a C3‐nucleophile and later as an acylating agent, through a metal‐catalyzed decarboxylative process, which enables the formation of the final lactone.
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中文翻译:

萘醌与β-芳基丙酮酸的多米诺反应:3-(萘醌基)萘呋喃-2(3H)-ones的合成

β-芳基丙酮酸衍生物与萘醌反应后显示出双重反应性,首先通过金属催化的脱羧过程充当C3-亲核试剂,然后充当酰化剂,从而形成最终的内酯。
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更新日期:2018-02-28
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