当前位置: X-MOL 学术Eur. J. Org. Chem. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Front Cover: Directed ortho‐Metalation of O‐Aryl N,N‐Dialkylcarbamates: Methodology, Anionic ortho‐Fries Rearrangement, and Lateral Metalation (Eur. J. Org. Chem. 4/2018)
European Journal of Organic Chemistry ( IF 2.8 ) Pub Date : 2018-01-10 , DOI: 10.1002/ejoc.201800016
M. A. Jalil Miah 1 , Mukund P. Sibi 2 , S. Chattopadhyay 3 , Oluwole B. Familoni 4 , Victor Snieckus 5
Affiliation  

The Front Cover shows a wheel centered on the aryl ortho‐lithiated O‐carbamate represented by the maple leaf (imagine a benzene ring) and by two ethyl hockey‐stick groups (both symbolic to Canada), the carbamate's partial history, its anionic equivalency to the venerable Fries rearrangement, and its rich chemistry. Follow the wheel from 12 o'clock in an R configuration passing through a carbamate used for treatment of a neuromuscular disease, through Karl Fries, and ending in directed ortho‐metalation (DoM), anionic ortho‐Fries rearrangement (AoF), and walking‐around‐the‐ring DoM – all very useful reactions for synthetic aromatic chemistry. More information can be found in the Full Papers (ejoc.201701142 and ejoc.201701143) by M. A. J. Miah, V. Snieckus et al.
image


中文翻译:

封面:N,N-二烷基氨基甲酸O-芳烃的定向邻位金属化:方法学,阴离子邻位炸薯条重排和侧向金属化(Eur.J.Org.Chem.4 / 2018)

前盖显示了一个轮子,其中心位于枫叶(想象成苯环)和两个乙基曲棍球棒基团(对加拿大而言都是象征性的)上代表的芳基甲酸酯化的O-氨基甲酸酯,氨基甲酸酯的部分历史,其阴离子当量对古老的薯条重新排列及其丰富的化学作用。遵循从12时的轮在穿过用于治疗神经肌肉病的,通过卡尔·弗里斯氨基甲酸酯R构型,并在引导结束-metalation(d Ò M),阴离子邻Fries重排(A ÒF)和环行DoM –所有对于合成芳族化学非常有用的反应。可以在MAJ Miah,V.Snieckus等人的论文全文(ejoc.201701142和ejoc.201701143)中找到更多信息。
图像
更新日期:2018-01-10
down
wechat
bug