当前位置: X-MOL 学术Microchim. Acta › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Microwave-assisted synthesis of highly luminescent N- and S-co-doped carbon dots as a ratiometric fluorescent probe for levofloxacin
Microchimica Acta ( IF 5.7 ) Pub Date : 2018-01-10 , DOI: 10.1007/s00604-017-2619-z
Huiyu Li , Yuan Xu , Jie Ding , Li Zhao , Tianyu Zhou , Hong Ding , Yanhua Chen , Lan Ding

AbstractUniform N- and S-co-doped carbon dots (NSCDs) with fluorescence quantum yields of up to 64% were synthesized via a one-step microwave-assisted method. Ammonium citrate and L-cysteine act as precursors, and synthesis is completed in 2.5 min using a 750 W microwave oven to give a 62% yield. The NSCDs show bright blue fluorescence (with excitation/emission peaks at 353/426 nm) and have narrow size distribution. On exposure to levofloxacin (LEV), the emission maximum shifts to 499 nm. This effect was used to design ratiometric (2-wavelength) assays for LEV. The fluorometric method (based on measurement of the fluorescence intensity ratio at 499 and 426 nm) has a detection limit of 5.1 μg·L−1 (3σ/k) and a linear range that extends from 0.01 to 70 mg·L−1. The method was applied to the determination of LEV in three kinds of spiked water samples and has recoveries in the range from 98.6 to 106.8%. The fluorescent probe described here is highly selective and sensitive. Graphical AbstractHighly luminescent N- and S-co-doped carbon dots were synthesized using AC (ammonium citrate) and Cys (L-cysteine) by microwave-assisted method, and were applied to the visual and ratiometric fluorescence determination of LEV (levofloxacin).

中文翻译:

微波辅助合成高发光 N 和 S 共掺杂碳点作为左氧氟沙星的比率荧光探针

摘要 通过一步微波辅助方法合成了荧光量子产率高达 64% 的均匀 N 和 S 共掺杂碳点 (NSCD)。柠檬酸铵和 L-半胱氨酸作为前体,使用 750 W 微波炉在 2.5 分钟内完成合成,产率为 62%。NSCD 显示出明亮的蓝色荧光(激发/发射峰位于 353/426 nm)并且具有窄的尺寸分布。暴露于左氧氟沙星 (LEV) 时,发射最大值移至 499 nm。这种效应用于设计 LEV 的比率(2 波长)测定。荧光法(基于在 499 和 426 nm 处测量荧光强度比)的检测限为 5.1 μg·L-1 (3σ/k),线性范围为 0.01 至 70 mg·L-1。该方法用于测定三种加标水样中的LEV,回收率在98.6%~106.8%之间。此处描述的荧光探针具有高度选择性和敏感性。图形摘要采用AC(柠檬酸铵)和Cys(L-半胱氨酸)通过微波辅助方法合成了高发光的N-和S-共掺杂碳点,并将其应用于LEV(左氧氟沙星)的视觉和比率荧光测定。
更新日期:2018-01-10
down
wechat
bug