Abstract The development of a novel polydopamine (PDA)-functionalized graphene nanoplatelets (GNPs)-based disposable sensor is described. The sensor was fabricated by drop-coating PDA@GNPs in polyethylene glycol (PEG) and poly(3,4-ethylenedioxythiophene (PEDOT):poly(styrenesulfonate) (PSS) aqueous suspension onto the working area of a screen-printed electrode (SPE). The final sensor, designated as PDA@GNPs/PPP/SPE, was characterized by scanning electron microscopy (SEM), Raman spectroscopy, Faradaic electrochemical impedance spectroscopy (FEIS) and cyclic voltammetry (CV). Mediated detection of hydrogen peroxide (H 2 O 2 ) via the redox properties of PDA was achieved. It showed excellent selectivity and sensitivity towards H 2 O 2 with a limit of detection and sensitivity of 0.55 µM (S/N = 3) and 3.0 µA mM −1 cm −2 , respectively. Thereafter, glucose oxidase (GOx) was immobilized onto the electrode to develop GOx/PDA@GNPs/PPP/SPE sensor. The glucose biosensor exhibited a limit of detection of 0.25 μM (S/N = 3) and a sensitivity of 0.51 μA μM −1 cm −2 ; thus, proving its potential suitability for bio-sensing applications.

中文翻译：

---

用于生物传感应用的聚多巴胺功能化石墨烯纳米血小板智能导电电极

摘要描述了一种新型聚多巴胺 (PDA) 功能化石墨烯纳米片 (GNP) 型一次性传感器的开发。该传感器是通过将聚乙二醇 (PEG) 和聚 (3,4-乙撑二氧噻吩 (PEDOT): 聚(苯乙烯磺酸) (PSS) 水悬浮液中的 PDA@GNP 滴涂到丝网印刷电极 (SPE最终的传感器，命名为PDA@GNPs/PPP/SPE，通过扫描电子显微镜（SEM）、拉曼光谱、法拉第电化学阻抗谱（FEIS）和循环伏安法（CV）进行表征。 2 O 2 ) 通过 PDA 的氧化还原特性实现。它对 H 2 O 2 显示出优异的选择性和灵敏度，检测限和灵敏度为 0.55 µM (S/N = 3) 和 3.0 µA mM -1 cm -2 ，分别。此后，将葡萄糖氧化酶 (GOx) 固定在电极上以开发 GOx/PDA@GNPs/PPP/SPE 传感器。葡萄糖生物传感器的检测限为 0.25 μM (S/N = 3)，灵敏度为 0.51 μA μM -1 cm -2 ；因此，证明了其对生物传感应用的潜在适用性。