A new Cu(OTf)₂‐Catalysed sequential reaction involving the oxidative ring opening of epoxides by the solvent DMSO and an oxa‐Michael addition of electron‐deficient alkenes has been developed. In this transformation, one new C=O bond and one new C–O bond are created. The sequential reaction allows the rapid and efficient synthesis of 4‐isochromanones in moderate to good yields under mild conditions.

中文翻译：

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通过Cu（OTf）2催化的顺序C = O和C-O键形成构建4-异色酮

已开发出一种新的Cu（OTf）₂催化的顺序反应，该反应涉及通过溶剂DMSO和缺电子烯烃的oxa-Michael加成环氧化物的氧化开环。在此转换中，创建了一个新的C = O键和一个新的C-O键。顺序反应可在温和条件下以中等至良好的收率快速有效地合成4-异苯并二氢呋喃。