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SERCA2b Cycles Its Way to UCP1-Independent Thermogenesis in Beige Fat.
Cell Metabolism ( IF 29.0 ) Pub Date : 2018-01-09 , DOI: 10.1016/j.cmet.2017.12.015
Emilio P Mottillo 1 , Vanesa D Ramseyer 1 , James G Granneman 1
Affiliation  

A new study in Nature Medicine, by Ikeda et al. (2017), reports that calcium cycling in beige adipocytes elevates energy expenditure and glucose oxidation in the absence of uncoupling protein 1. Thermogenic calcium cycling in beige fat is mediated by SERCA2b and improves cold tolerance and metabolic status.

中文翻译:

SERCA2b循环产生米色脂肪中不依赖UCP1的生热作用。

池田等人在自然医学领域的一项新研究。(2017年)报道,在缺乏解偶联蛋白1的情况下,米色脂肪细胞中的钙循环会增加能量消耗和葡萄糖氧化。米色脂肪中的热钙循环是由SERCA2b介导的,并改善了耐寒性和代谢状态。
更新日期:2018-01-09
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